The latest paper on transgene insertion has been published in Biotechnology and Genetic Engineering Reviews (vol 23, December 2006, pp 209-237).
Title: Transformation-induced Mutations in Transgenic Plants: Analysis and Biosafety Implications
By ALLISON K. WILSON, JONATHAN R. LATHAM AND RICARDA A. STEINBRECHER
It is the most comprehensive and up to date resource available anywhere on the characteristics of transgene integration.
It is available as a pdf c/o the Bioscience Resource Project website - http://www.bioscienceresource.org/docs/BSR-2-BGERvol23.pdf
The work of this group of independent scientists on so-called "genome scrambling" has been extremely important in revealing how the genetic engineering of crops not only lacks precision but causes large scale genetic rearrangements of host DNA at transgene insertion sites, as well as large numbers of mutations scattered throughout the genome of each new transgenic plant. The significance of all this genetic damage is that the food safety of edible crops relies crucially on genetic stability.
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